By Abbott Alison / Source: Nature.com
Severely depressed patients who do not respond to conventional therapy may be helped by deep brain stimulation (DBS), according to the most-extensive study to date of the experimental procedure.
In a clinical trial in Toronto, Canada, 12 out of 20 patients who had stimulating electrodes placed in a brain area called the subcallosal cingulated gyrus showed significant improvement in their depression, with seven of them going into full remission.
The benefits lasted at least a year, according to the results published this week in the journal Biological Psychiatry1. Patients in the study had failed to respond to cognitive therapy, antidepressant drugs and electroconvulsant therapy.
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